Renal involvement in COVID-19: a review of the literature

Marco Giuseppe Migliaccio,1,* Marco Di Mauro,1,* Riccardo Ricciolino,1 Giorgio Spiniello,1 Vincenzo Carfora,1 Nicoletta Verde,1 Filiberto Fausto Mottola,1 Nicola Coppola2 On behalf of the Vanvitelli COVID-19 Group

1Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Naples, Italy; 2Department of Mental Health and Public Medicine, Infectious Diseases Unit, University of Campania “Luigi Vanvitelli”, Naples, Italy

* These authors have contributed equitably to this work

Correspondence: Nicola Coppola
Department of Mental Health and Public Medicine, Infectious Diseases Unit, University of Campania “Luigi Vanvitelli”, Via: L. Armanni 5, Naples, 80131, Italy
Phone +39 081 5666719
Fax +39 081 5666013
Email nicola.coppola@unicampania.it

Abstract: Kidney damage can be a serious complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsening the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair kidney function, proving the complexity of viral activity and the resulting immune response. We have summarized the evidence from the literature on the prevalence of renal impairment, pathogens and its management.

Keywords: kidney injury, acute kidney injury, COVID-19, SARS-CoV-2

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