Covid: rare “ breakthrough infections ” reported in fully vaccinated people

The risk of contracting Covid after receiving two doses of the vaccine remains extremely low, according to a new US study.

Two rare cases of Covid-19 in fully vaccinated people – also known as ‘breakthrough infection’ – have been reported in the New England Journal of Medicine study Wednesday.

The study found two women out of 417 Rockefeller University employees who had been vaccinated with the Pfizer or Moderna jabs, tested positive for coronavirus.

Both women reportedly exhibited mild symptoms and recovered quickly.

The Moderna vaccine is the third coronavirus vaccine to be approved for use in the UK, after those from Pfizer and Oxford / AstraZeneca. Credit: PA Images

Who were the people who had the so-called “rupture infection” and do they have any health problems?

A healthy 51-year-old woman who received her second dose of Moderna vaccine on February 19 was one of the cases who had a “breakthrough infection.”

Nineteen days later, she tested positive for Covid-19 on March 10 after developing symptoms.

The other breakout of infection was in a healthy 65-year-old woman who received her second dose of the Pfizer vaccine on February 9.

She later learned that her partner, who was not vaccinated, had tested positive for Covid-19 on March 3.

In the following days, the woman developed her own symptoms. She tested positive for Covid-19 on March 17.

Should I be concerned about ‘revolutionary infections’ from Covid?

No. These “breakthrough infections” of fully vaccinated people contracting Covid-19 are very rare.

A co-author of the study, Dr Robert Darnell, a senior physician at Rockefeller University in New York, said there was no major cause for concern in either case.

He said: “They certainly didn’t need to be hospitalized. They had cases of Covid-19 at home.”

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Have there been any other cases of “rupture infections”?

the Centers for Disease Control and Prevention (CDC) said last week it had received reports of around 5,800 breakthrough infections in more than 75 million fully vaccinated people in the United States.

The CDC said “rupture infections” have occurred in people of all ages who have been vaccinated, but more than 40% of infections have been in people 60 years of age or older.

The health agency also said there is evidence that a full vaccination can make the Covid infection less severe.

Can Covid Variants Cause “Rupture Infections”?

Scientists have found variants with several differences from the original Covid-19 that caused groundbreaking infections.

The South African variant which infected one of the patients had the E484K mutation, was first found in the B.1.351 variant.

People take part in coronavirus surge tests on Clapham Common after new cases of the South African variant are found in two boroughs of south London Credit: Kirsty O’Connor / PA

E484K has been called an “escape mutant” because it has shown that it may be able to escape some of the antibodies produced by coronavirus vaccines.

One of the mutations found in the infections of the two study participants included D614G, which emerged early in the pandemic.

What Did British Scientists Say About Revolutionary Infections?

Professor Graham Medley, of the London School of Hygiene & Tropical Medicine and chairman of Spi-M, said there would likely be “a breakthrough in immunity”, but it is too early to tell because the vaccine does not ‘hasn’t been around long enough.

He said: “The vaccine hasn’t been released to people in the real world… only in December it started… so we don’t know what effect it’s going to have in three, four months and that’s the real one. unknown.

“So it’s a matter of real uncertainty.”

He added: “The only thing we can be sure of is that we don’t know exactly what’s going to happen, but we do know that because the vaccine is not 100% effective, there will be a problem. transmission, and there will be a breakthrough in immunity. ”


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